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Cat. No. Product Name Species Expression System
TMPJ-01020 GFER Protein, Human, Recombinant (His)

Augmenter of liver regeneration,FAD-linked sulfhydryl oxidas...

Human E. coli
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ER...
TMPY-00368 ALR Protein, Human, Recombinant (His)

HPO,ERV1,HERV1,ALR,HSS,HPO2,growt...

Human HEK293 Cells
Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis and respiratory chain deficiency in 3 siblings born to consanguineous Moroccan parents by homozygosity mapping and candidate gene approach. Using homozygosity mapping, we discovered that a mutation in the GFER gene causes an infantile mitochondrial disorder.

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GFER Protein, Human, Recombinant (His)
Cat.No: TMPJ-01020
Species: Human
Expression System: E. coli
ALR Protein, Human, Recombinant (His)
Cat.No: TMPY-00368
Species: Human
Expression System: HEK293 Cells
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