Cat. No. | Product Name | Target | Signaling Pathways |
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T79541 |
HDAC-IN-61
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HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
HDAC-IN-61(compound 12k)为口服生效的HDAC抑制剂,表现出针对Bel-7402细胞线的明显抗癌活性,其IC50值仅为30 nM,适用于癌症研究领域。 | |||
T36110 |
L-Pyrohomoglutamic Acid
|
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L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors. 1.Pomplun, S., Wang, Y., Kirschner, A., et al.Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs)Angew. Chem. Int. Ed.54(1)345-348(2015) 2.Taddei, M., Cini, E., Giannotti, L., et al.Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors... |