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Cat. No.	Product Name	Target	Signaling Pathways
T72872	HDAC/BET-IN-1	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HDAC/BET-IN-1表现出对HDAC1 (IC50= 0.163 μM) 和HDAC6 (IC50= 0.067 μM) 的亚微摩尔级别抑制作用，以及对BRD4 (Ki= 0.076 μM) 的抑制活性，同时也显示出显著的抗白血病活性。
T36103	TW9 TW9
	TW9 is a dual inhibitor of bromodomain 2 (BD2) in bromodomain-containing protein 4 (BRD4) and histone deacetylase 1 (HDAC1; IC50s = 0.074 and 0.29 μM, respectively).1It is selective for BD2 over BD1 in BRD4 (IC50= 0.72 μM) and for HDAC1 over HDAC2 (IC50= 2.5 μM). TW9 (50 nM) induces apoptosis in, and inhibits proliferation of, MIA PaCa-2 pancreatic cancer cells. It induces cell cycle arrest at the G1phase in HPAC pancreatic cancer cells when used at a concentration of 2 μM. TW9 acts synergistica...