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Cat. No. Product Name Target Signaling Pathways
T5829 H4 Receptor antagonist 1

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
H4 Receptor antagonist 1 是选择性组胺 H4受体反向激动剂,其IC50值为19 nM。
T38634 Histamine H4 receptor antagonist-1

Histamine H4 receptor antagonist-1

Histamine H4 receptor antagonist-1 is a potent antagonist of the histamine H4 receptor.
T11532 H4R antagonist 1

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
H4R antagonist 1 is a highly selective histamine H4 receptor (H4R) antagonist (IC50: 27 nM). H4R antagonist 1 does not show any noticeable binding affinity to other subtypes of histamine receptors, H1R, H2R, and H3R.
T79786 H4R antagonist 2

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
H4R antagonist 2 是Furo[3,2-d]嘧啶衍生的有效H4R拮抗剂,主要用于类风湿性关节炎的研究。
T61011 Izuforant

Izuforant (JW1601) (Compound 24) 具有有效的抗炎和止痒活性。 Izuforant 对人血清素3受体 (h5-HT3R) 具有结合亲和力,IC50值为 9.1 μM。它也是组胺 H4 受体 (H4R) 的口服活性拮抗剂,对人 H4R 的IC50值为 36 nM。
T38323 A-943931 (hydrochloride hydrate)

A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1In vivo, A-943931 inhibits scratching induced by clobenpropit in mice (ED50= 26 μmoles/kg, i.p.). 1.Milicic, I., Witte, D.G., Miller, T.L., et al.Identification of two potent and selective histamine H4 receptor antagonists with antipruritic activityFASEB J.23(S1)760.768-760.768(2009)

化合物

H4 Receptor antagonist 1
Cat.No: T5829
Synonym:
Target: Histamine Receptor
Histamine H4 receptor antagonist-1
Cat.No: T38634
Synonym: Histamine H4 receptor antagonist-1
Target:
H4R antagonist 1
Cat.No: T11532
Synonym:
Target: Histamine Receptor
H4R antagonist 2
Cat.No: T79786
Synonym:
Target: Histamine Receptor
Izuforant
Cat.No: T61011
Synonym:
Target:
A-943931 (hydrochloride hydrate)
Cat.No: T38323
Synonym:
Target:
TargetMol Loading
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