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Cat. No. Product Name Target Signaling Pathways
T7778 Glypromate

Gly-Pro-Glu,甘氨酰-脯氨酰-谷氨酸

NMDAR Neuroscience
Glypromate (Gly-Pro-Glu) 是一种神经保护剂,是一种弱 NMDA 受体激动剂。
T8761 [Leu15]-Gastrin I human

Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2

Others Others
[Leu15]-Gastrin I human (Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2) 基因编码人体内的蛋白质 [Leu15]-胃泌素 I。在人类染色体中,GAST 基因定位于 17q21.2。胃窦中的 G 细胞产生 [Leu15]-胃泌素 I 的前体前胃泌素。前胃泌素经过裂解和加工产生胃泌素,它对整个胃肠道上皮细胞具有营养作用。胃泌素对消化系统的生长至关重要,并刺激壁细胞产生胃酸。胃泌素通过称为胆囊收缩素(CCK) 或 CCK-B 受体 (CCK-BR) 的 G 蛋白偶联受体发挥其功能。胃泌素的释放受到食物的刺激,尤其是蛋白质饮食,并受到非常低的 pH 值的抑制。萎缩性胃炎、幽门螺杆菌感染和长期服用质子泵抑制剂感染可能导致胃泌素过度表达。胃腺癌显示高水平的胃泌素。
T83720 Biotin-Crosstide TFA

Biotin-Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly-OH

Biotin-crosstide是Akt底物crosstide的生物素化形式。
TP2412 Tanurmotide

Human lymphocyte antigen 6k-(101-111)-peptide.,Arg-tyr-cys-asn-leu-glu-gly-pro-pro-ile

Tanurmotide is a bioactive chemical.
T36405 Pro-Adrenomedullin (153-185), human

Pro-Adrenomedullin (153-185), human,H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH

Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma in 19931. AM was initially identified as a vasodilator, some have cited this as the most potent endogenous vasodilatory peptide found in the body2. Differences in opinion regarding the ability of AM to relax vascular tone arises from the differences in the model system...
TP1305 LEP(116-130)(mouse)

Others Others
LEP(116-130)(mouse) 是合成的瘦素肽片段之一。
TP1092 Myelin Basic Protein (MBP) (68-82), guinea pig

MBP (68-82), guinea pig,豚鼠髓磷脂碱性蛋白片段68-82

Others Others
Myelin Basic Protein (MBP) (68-82), guinea pig 是一种髓鞘碱性蛋白 (MBP) 的片段。
TP2187 Ribosomal protein L3 peptide (202-222) amide

Others Others
Ribosomal protein L3 peptide (202-222) is a peptide with the sequenceH2N-Met-Ser-His-Arg-Lys-Tyr-Glu-Ala-Pro-Arg-His-Gly-His-Leu-Gly-Phe-Leu-Pro-Arg-Lys-Arg-amide, MW=2573.
TP2257 Histone-H2A-(107-122)-Ac-OH

Others Others
Histone-H2A-(107-122)-Ac-OH is a peptide with the sequence Ac-Gly-Val-Leu-Pro-Asn-Ile-Gln-Ala-Val-Leu-Leu-Pro-Lys-Lys-Thr-Glu-OH, MW= 1762.1. Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells.
TP2177 Amyloid Precursor C-Terminal Peptide

Others Others
Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose am
TP2212 a-MSH, amide

Others Others
a-MSH, amide is a peptide with the sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, MW= 1664.9. The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of peptide hormones that are produced by c
TP2176 amyloid A protein fragment [Homo sapiens]

Others Others
Amyloid A proteins (H2N-Ala-Gly-Leu-Pro-Glu-Lys-Tyr-OH) are a family of apolipoproteins associated with high-density lipoprotein in plasma. Different isoforms of SAA are expressed constitutively at different levels or in response to inflammatory stimuli.
T83825 Trofinetide acetate

NNZ-2566

Trofinetide是一种衍生自具有神经保护作用的三肽Gly-Pro-Glu的化合物,后者是胰岛素样生长因子-1(IGF-1)的N-端序列。在10 nM的浓度下使用时,它能减少由蛋白磷酸酶抑制剂奥卡达酸在原代大鼠胚胎纹状体神经元中引起的细胞死亡。Trofinetide在一种由穿透性弹道样脑损伤引起的大鼠神经炎症模型中减少了编码IL-1β、TNF-α、IL-6和E-selectin的mRNA的脑表达。在通过中脑动脉闭塞(MCAO)引起的大鼠脑损伤模型中,以30和60 mg/kg的剂量给药时,它减少了皮层和纹状体梗塞区域。Trofinetide(每天100 mg/kg)减少了树突棘的数量,并逆转了在fmr1-/-敲除小鼠脆性X综合征模型中的社交识别和情景恐惧条件反射的缺陷,同时也减少了睾丸重量的增加。含有Trofinetide的制剂已被用于治疗Rett综合征。

化合物

Glypromate
Cat.No: T7778
Synonym: Gly-Pro-Glu,甘氨酰-脯氨酰-谷氨酸
Target: NMDAR
[Leu15]-Gastrin I human
Cat.No: T8761
Synonym: Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2
Target: Others
Biotin-Crosstide TFA
Cat.No: T83720
Synonym: Biotin-Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly-OH
Target:
Tanurmotide
Cat.No: TP2412
Synonym: Human lymphocyte antigen 6k-(101-111)-peptide.,Arg-tyr-cys-asn-leu-glu-gly-pro-pro-ile
Target:
Pro-Adrenomedullin (153-185), human
Cat.No: T36405
Synonym: Pro-Adrenomedullin (153-185), human,H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH
Target:
LEP(116-130)(mouse)
Cat.No: TP1305
Synonym:
Target: Others
Myelin Basic Protein (MBP) (68-82), guinea pig
Cat.No: TP1092
Synonym: MBP (68-82), guinea pig,豚鼠髓磷脂碱性蛋白片段68-82
Target: Others
Ribosomal protein L3 peptide (202-222) amide
Cat.No: TP2187
Synonym:
Target: Others
Histone-H2A-(107-122)-Ac-OH
Cat.No: TP2257
Synonym:
Target: Others
Amyloid Precursor C-Terminal Peptide
Cat.No: TP2177
Synonym:
Target: Others
a-MSH, amide
Cat.No: TP2212
Synonym:
Target: Others
amyloid A protein fragment [Homo sapiens]
Cat.No: TP2176
Synonym:
Target: Others
Trofinetide acetate
Cat.No: T83825
Synonym: NNZ-2566
Target:
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