Cat. No. | Product Name | Target | Signaling Pathways |
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T37908 |
Glucocorticoid receptor agonist-1
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Glucocorticoid Receptor | Endocrinology/Hormones |
Glucocorticoid receptor agonist-1是一种强效糖皮质激素受体激动剂,其 IC50 值为 2.8 nM。 | |||
T74116 | Glucocorticoid receptor agonist-1 Ala-Ala-Mal | ||
Glucocorticoid receptoragonist-1 Ala-Ala-Mal (化合物 88) 是一种糖皮质激素,是糖皮质激素受体激动剂。Glucocorticoid receptoragonist-1 Ala-Ala-Mal 可与Adalimumab 偶联制备ADC。 | |||
T82303 | Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA | ||
Glucocorticoid receptor agonist-1 phosphate Gly-Glu (TFA) 是用于抗体-药物偶联物 (Antibody-Drug Conjugates (ADCs)) 合成的可降解 Linker。 | |||
T77835 |
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br
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Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br 为ADC linker,适用于ABBV-154、ABBV-927及ABBV-368或相似化合物的合成。 | |||
T75130 | Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br | ||
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br 作为一种Drug-linker conjugates for ADC,主要用于抗CD40抗体活性分子偶联物 (ADCs) 的合成, 充当反应试剂。 | |||
T75016 | Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal | ||
Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 是一种糖皮质激素受体激动剂。Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 可用于抗 CD40抗体偶联活性分子(ADC)。Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 可用于炎症和免疫调节的研究。 | |||
T40808 |
Glucocorticoids receptor agonist 1
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Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining insulin secretion function. | |||
T74697 | Glucocorticoid receptor agonist-2 | ||
Glucocorticoid receptoragonist-2 (compound 21) 作为一种糖皮质激素受体激动剂,具有 6.6 nM 的 IC50 值,主要用于抗炎 ADC 分子的合成。同时,它也是 ABBV-3373 的活性对照物。 | |||
T77869 |
Glucocorticoid receptor agonist-2 Ala-Ala-Mal
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Glucocorticoid receptor agonist-2 Ala-Ala-Mal(化合物79)是ABBV-3373的活性对照,可用于合成抗炎ADC分子。 | |||
T14374 |
AZD2906
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AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow. | |||
T75009 | PPARγ/GR modulator 1 | ||
PPARγ/GR modulator 1 是一种口服活性的 PPARγ和糖皮质激素受体 (GR) 的双动激动剂,Ki 值分别为 3.3 和 33.6 μM。PPARγ/GR modulator 1 可用于研究代谢疾病,例如糖尿病。 |