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Cat. No. Product Name Target Signaling Pathways
T0127 Glimepiride

Glimperide,HOE-490,格列美脲

Potassium Channel Membrane transporter/Ion channel
Glimepiride (HOE-490) 是一种中长效的磺酰脲类抗糖尿病化合物,其 ED50=182 μg/k。
T64332 Glimepiride sulfonamide

Immunology/Inflammation related Immunology/Inflammation
Glimepiride sulfonamide 是一种抗炎活性化合物。
T35641 trans-hydroxy Glimepiride

trans-hydroxy Glimepiride is an active metabolite of the sulfonylurea glimepiride .1It is formed from glimepiride primarily in the liver by the cytochrome P450 (CYP) isoform CYP2C9. 1.Langtry, H.D., and Balfour, J.A.Glimepiride. A review of its use in the management of type 2 diabetes mellitusDrugs55(4)563-584(1998)
T35640 trans-carboxy Glimepiride

trans-carboxy Glimepiride is a metabolite of the sulfonylurea glimepiride .1It is formed from glimepiride in a two-step process mediated by the cytochrome P450 (CYP) isoform CYP2C9 and cytosolic enzymes. 1.Noh, K., Kim, E., Jeong, T.C., et al.Simultaneous determination of glimepiride and its metabolites in human plasma by liquid chromatography coupled to a tandem mass spectrometryArch. Pharm. Res.34(12)2073-2078(2011)
T71284 Glimepiride urethane

Glimepiride urethane is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, glimepiride increases the activity of intracellular insulin receptors. Glimepiride increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases prote...

化合物

Glimepiride
Cat.No: T0127
Synonym: Glimperide,HOE-490,格列美脲
Target: Potassium Channel
Glimepiride sulfonamide
Cat.No: T64332
Synonym:
Target: Immunology/Inflammation related
trans-hydroxy Glimepiride
Cat.No: T35641
Synonym:
Target:
trans-carboxy Glimepiride
Cat.No: T35640
Synonym:
Target:
Glimepiride urethane
Cat.No: T71284
Synonym:
Target:
TargetMol Loading
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