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Cat. No. | Product Name | Target | Signaling Pathways |
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T80951 |
Trevogrumab
REGN-1033 |
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Trevogrumab (REGN-1033) 是针对GDF8(即生长分化因子8,亦称为肌肉生长抑制素)的单克隆抗体。该化合物目前主要用于研究包括废用性萎缩、慢性疾病以及饮食及营养摄入变化等原因引起的肌肉减少症。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04534 |
GDF-8 Protein, Mouse, Recombinant (hFc)
骨肉瘤源生长因子,Cmpt,myostatin,Gdf8 |
Mouse | HEK293 Cells |
GDF-8 / Myostatin / MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF-8 / Myostatin / MSTN is highly expressed in skeletal muscle, and myostatin loss-of-function le... | |||
TMPJ-00663 |
GDF-8 Protein, Human/Mouse/Rat, Recombinant
骨肉瘤源生长因子,Gdf8,Mstn,GDF-8... |
Human,Mouse,Rat | HEK293 Cells |
Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically a... | |||
TMPY-01814 |
GASP-1/WFIKKN2 Protein, Human, Recombinant (His)
WFIKKNRP,GASP-1,hGASP-1,WFDC20B,WAP, follistatin/kazal, immu... |
Human | HEK293 Cells |
WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2 and GASP1, is a secreted protein that belongs to the WFIKKN family. WFIKKN2 contains two BPTI/Kunitz inhibitor domains, one Ig-like C2-type (immunoglobulin-like) domain, one Kazal-like domain, one NTR domain and one WAP domain. WFIKKN2 ... |