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Targets Recommended: Galectin

4

抑制剂 & 化合物

13

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T79380 Galectin-3/galectin-8-IN-1

Galectin Immunology/Inflammation
Galectin-3/galectin-8-IN-1 (Compound 53) 是抑制Galectin-3和galectin-8C末端结构域的双重抑制剂,其Kd值分别为4.12 μM和6.04 μM。该化合物有效抑制MRC-5肺成纤维细胞的迁移,可用于癌症和组织纤维化的研究。
T79381 Galectin-3/galectin-8-IN-2

Galectin Immunology/Inflammation
Galectin-3/galectin-8-IN-2(Compound 57)是一种针对Galectin-3和galectin-8C末端结构域的双重抑制剂,其Kd值分别为12.8 μM和2.06 μM。该化合物能够抑制MRC-5肺成纤维细胞的迁移,适用于癌症和组织纤维化研究领域。
T61014 Galectin-8-IN-1

Galectin-8-IN-1 是galectin-8N-末端结构域的选择性配体,Kd 值为 48 μM。Galectin-8-IN-1 的选择性是 galectin-3 的 15 倍,甚至优于其他哺乳动物的 galectins。
T63485 Apoptosis inducer 8

Apoptosis inducer 8 是一种galectin-1 (gal-1)介导的凋亡 (apoptosis) 诱导剂,也是一种PET 显像剂,能够明显减少 gal-1 蛋白水平,可用于全球主要的肺癌的研究。

化合物

Galectin-3/galectin-8-IN-1
Cat.No: T79380
Synonym:
Target: Galectin
Galectin-3/galectin-8-IN-2
Cat.No: T79381
Synonym:
Target: Galectin
Galectin-8-IN-1
Cat.No: T61014
Synonym:
Target:
Apoptosis inducer 8
Cat.No: T63485
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00654 LGALS8 Protein, Human, Recombinant

Prostate Carcinoma Tumor Antigen 1,Po66-CBP,Galectin

Human E. coli
The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. Although they are localized primarily in the cytoplasm and lack a classical signal peptide, galectins can also be...
TMPY-02611 Galectin-8 Protein, Human, Recombinant

lectin, galactoside-binding, soluble, 8,PCTA-1,Po66...

Human E. coli
Galectin-8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 35.5 kDa and the accession number is AAF19370.1.
TMPY-02773 Galectin-8 Protein, Rat, Recombinant (GST)

lectin, galactoside-binding, soluble, 8

Rat E. coli
Galectin-8 Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 63.2 kDa and the accession number is Q6IN24.
TMPY-02326 Galectin-8 Protein, Human, Recombinant (GST)

PCTA1,Po66-CBP,PCTA-1,lectin, galactoside-binding, soluble, ...

Human E. coli
Galectin-8 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 62.7 kDa and the accession number is AAF19370.1.
TMPH-01363 Galectin-8/LGALS8 Protein, Human, Recombinant (GST)

Human E. coli
Galectin-8/LGALS8 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 62.8 kDa and the accession number is O00214.
TMPY-04123 CEACAM1 Protein, Human, Recombinant (His & hFc)

CEACAM‑1,carcinoembryonic antigen-related cell adhesion mole...

Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPH-01705 Mucin-1/MUC1 Protein, Human, Recombinant (His)

Human E. coli
Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPJ-00808 CD45RA Protein, Human, Recombinant (His)

PTPRC,CD45R,CD45,LCA,protein tyrosine phosphatase, receptor ...

Human HEK293 Cells
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPJ-00828 Tau-F Protein, Human, Recombinant

Neurofibrillary tangle protein,Paired helical filament-tau,M...

Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def...
TMPY-00717 CEACAM1 Protein, Human, Recombinant (His)

CEACAM‑1,BGP1,BGP,carcinoembryonic antigen-related cell adhe...

Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.
TMPY-06707 Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

ADMCKD,PEMT,KL-6,ADMCKD1,H23AG,mucin 1, cell surface associa...

Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-01330 CD299 Protein, Human, Recombinant (His & Flag)

DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami...

Human HEK293 Cells
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc)

CTFγ,amyloid beta (A4) precursor protein,AAA,ABPP,CVAP,APPI,...

Human HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.

重组蛋白

LGALS8 Protein, Human, Recombinant
Cat.No: TMPJ-00654
Species: Human
Expression System: E. coli
Galectin-8 Protein, Human, Recombinant
Cat.No: TMPY-02611
Species: Human
Expression System: E. coli
Galectin-8 Protein, Rat, Recombinant (GST)
Cat.No: TMPY-02773
Species: Rat
Expression System: E. coli
Galectin-8 Protein, Human, Recombinant (GST)
Cat.No: TMPY-02326
Species: Human
Expression System: E. coli
Galectin-8/LGALS8 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01363
Species: Human
Expression System: E. coli
CEACAM1 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-04123
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01705
Species: Human
Expression System: E. coli
CD45RA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00808
Species: Human
Expression System: HEK293 Cells
Tau-F Protein, Human, Recombinant
Cat.No: TMPJ-00828
Species: Human
Expression System: E. coli
CEACAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00717
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)
Cat.No: TMPY-06707
Species: Human
Expression System: HEK293 Cells
CD299 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-01330
Species: Human
Expression System: HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00668
Species: Human
Expression System: HEK293 Cells
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