Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T64394 |
GW 833972A
|
Cannabinoid Receptor | GPCR/G Protein |
GW 833972A 是一种选择性的 CB2 受体激动剂。GW 833972A 对诱导神经去极化具有抑制作用,且在动物模型中对柠檬酸引起的咳嗽具有抑制作用。 | |||
T68904 | GW-833972A free base | ||
GW833972 is a CB2 Agonist. GW 833972A inhibited capsaicin-induced depolarization of the human and guinea-pig and prostaglandin E(2) (PGE(2)) and hypertonic saline-induced depolarization of the guinea-pig isolated vagus nerve in vitro. GW 833972A also inhibited citric acid-induced cough but not plasma extravasation in the guinea-pig and this effect was blocked by a CB(2) receptor antagonist. |