Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6151 |
GW 501516
Cardarine,GW501516,GW 1516,GSK-516,Endurobol |
PPAR; Autophagy | Autophagy; DNA Damage/DNA Repair; Metabolism |
GW 501516 (Endurobol) 是一种有效且高度特异性的 PPARβ/δ 激动剂,EC50值为 1 nM,选择性是 hPPARα/γ 的 1000 倍。 | |||
T68302 |
KD3010 tosylate
|
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KD-3010 is a peroxisome proliferator-activated receptor delta agonist potentially for the treatment of diabetes and obesity. KD-3010 dramatically ameliorates liver injury induced by carbon tetrachloride (CCl(4)) injections. Deposition of extracellular matrix proteins was lower in the KD3010-treated group than in the vehicle- or GW501516-treated group. Interestingly, profibrogenic connective tissue growth factor was induced significantly by GW501516, but not by KD-3010, following CCl(4) treatmen... |