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Cat. No. Product Name Target Signaling Pathways
T9766 GW590735

PPAR DNA Damage/DNA Repair; Metabolism
GW590735 是一种有效的选择性 PPARα 激动剂,对 PPARα 的 EC50 为 4 nM,比 PPARδ 和 PPARγ 的选择性至少高 500 倍。 GW590735 可用于血脂异常研究。
T69408 GW590735 sodium

GW590735 is a potent and selective agonist of PPARα with an EC50 value of 4 nM for the expression a GAL4-responsive reporter gene and at least 500-fold selectivity versus PPARγ and PPARδ. GW590735 significantly increased HDL cholesterol, decreased LDL and VLDL cholesterol, and significantly reduced triglycerides. Maximal increases in HDL cholesterol were 37%, 53%, and 84% with fenofibrate, torcetrapib, and GW590735, respectively.

化合物

GW590735
Cat.No: T9766
Synonym:
Target: PPAR
GW590735 sodium
Cat.No: T69408
Synonym:
Target:
TargetMol Loading
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