Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15434 | GSK2798745 | TRP/TRPV Channel | Membrane transporter/Ion channel |
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in research for the treatment of pulmonary edema associated with congestive heart failure. |