Cat. No. | Product Name | Target | Signaling Pathways |
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T71069 |
GSK1842799 HCl
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GSK1842799 is a selective S1P1 receptor agonist for multiple sclerosis. Upon phosphorylation, GSK1842799 showed subnanomole S1P1 agonist activity with >1000× selectivity over S1P3. GSK1842799 demonstrated good oral bioavailability. On the basis of the favorable in vitro ADME and in vivo PK/PD properties as well as broad toxicology evaluations, GSK1842799 was selected as a candidate for further clinical. | |||
T71067 |
MK-1775 hemihydrate
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MK-1775 hemihydrate is a WEE1 inhibitor with potential antineoplastic sensitizing activity. |