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Cat. No. Product Name Target Signaling Pathways
T11500L GSK3368715 dihydrochloride

EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl

Histone Methyltransferase Chromatin/Epigenetic
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) 是一种具有口服活性和高效性的 I 型蛋白精氨酸甲基转移酶 (PRMTs) 抑制剂 ,具有抗癌和抗肿瘤活性,抑制PRMT1,PRMT3,PRMT4,PRMT6,PRMT8的活性,可用于研究晚期实体肿瘤。
T11500 GSK3368715

EPZ019997

Histone Methyltransferase Chromatin/Epigenetic
GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s: 3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). It has strong anti-cancer activity.
T22342 GSK3368715 3HCl

EPZ019997 3HCl,GSK3368715(EPZ019997)

Histone Methyltransferase Chromatin/Epigenetic
GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM.

化合物

GSK3368715 dihydrochloride
Cat.No: T11500L
Synonym: EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl
Target: Histone Methyltransferase
GSK3368715
Cat.No: T11500
Synonym: EPZ019997
Target: Histone Methyltransferase
GSK3368715 3HCl
Cat.No: T22342
Synonym: EPZ019997 3HCl,GSK3368715(EPZ019997)
Target: Histone Methyltransferase
TargetMol Loading
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