Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11486 |
GSK2807 Trifluoroacetate
|
Histone Methyltransferase | Chromatin/Epigenetic |
GSK2807 Trifluoroacetate 是一种选择性和 SAM 竞争性的 SMYD3 抑制剂,IC50为 130 nM,Ki 值为 14 nM。 | |||
T69738 |
GSK-2807 free base
|
||
GSK2807 is a potent and selective, SAM-competitive inhibitor of SMYD3 (Ki = 14 nM). GSK2807 bridges the gap between the SAM-binding pocket and the substrate lysine tunnel of SMYD3. GSK2807 may be useful for cancer treatment. |