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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T68568 Encequidar, HCl

Encequidar, also known as HM-30181, is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. Encequidar showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). Encequidar is currently under clinical trials.
T72678 P-gp inhibitor 4

P-gp inhibitor 4 是一种选择性的 P-glycoprotein 调节剂,EC50值为 94 nM。P-gp inhibitor 4 增加药物通过胃肠道屏障的能力,恢复 doxorubicin 在耐药癌细胞中的毒性。
T75766 GP(33-41) TFA

GP(33-41) TFA 是一种由 9 个氨基酸残基组成的多肽,它是淋巴细胞性脉络丛脑膜炎病毒 GP1 抗原决定基中的序列。GP(33-41) TFA 能够上调 RMA-S (Db Kb) 细胞表面 H-2Db 分子,SC50值为 344 nM。

化合物

Encequidar, HCl
Cat.No: T68568
Synonym:
Target:
P-gp inhibitor 4
Cat.No: T72678
Synonym:
Target:
GP(33-41) TFA
Cat.No: T75766
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01262 TROP-2 Protein, Human, Recombinant (His)

TROP2,M1S1,GA733-1,TROP-2,GA7331,tumor-associated calcium si...

Human HEK293 Cells
TROP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.4 kDa and the accession number is P09758.
TMPY-06972 TROP-2 Protein, Human, Recombinant (hFc)

EGP-1,GA733-1,tumor-associated calcium signal trans...

Human HEK293 Cells
TROP-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is NP_002344.2.
TMPY-00946 TROP-2 Protein, Human, Recombinant (His & hFc)

GP50,TACD2,GA733-1,M1S1,GA7331,EGP

Human HEK293 Cells
TROP-2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 55.7 kDa and the accession number is P09758.
TMPY-06378 TROP-2 Protein, Human, Recombinant (His & Avi), Biotinylated

EGP-1,GA733-1,GP50,TACD2,TROP2,E<...

Human HEK293 Cells
TROP-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 31.14 kDa and the accession number is NP_002344.2.
TMPY-06720 TROP-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated

GA733-1,EGP1,GP50,TROP-2,GA7331,E...

Human HEK293 Cells
TROP-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 56.42 kDa and the accession number is NP_002344.2.

重组蛋白

TROP-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01262
Species: Human
Expression System: HEK293 Cells
TROP-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06972
Species: Human
Expression System: HEK293 Cells
TROP-2 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00946
Species: Human
Expression System: HEK293 Cells
TROP-2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06378
Species: Human
Expression System: HEK293 Cells
TROP-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06720
Species: Human
Expression System: HEK293 Cells
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