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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T76317 [His1,Nle27] GHRF (1-32), amide, human

[His1,Nle27] GHRF (1-32), amide, human为一种生长激素释放激素（GHRH）类似物，对GHRHR受体具有较好的亲和力。
T40234 Ghrelin receptor full agonist-2

Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.
TP1393 rGHRH(1-29)NH2

RGHRH (1-29)NH2 is a synthetic peptide that stimulates the secretion of growth hormone (GH).
T82322 GHRF, mouse

Mouse growth hormone-releasing factor
GHRF, mouse为含44个氨基酸的小鼠生长激素释放肽，能够促进生长激素的释放与合成。
T75928 des-​Gln14-​Ghrelin TFA

des-Gln14-Ghrelin TFA为生长激素促分泌受体的第二个内源性配体。该化合物能在CHO-GHSR62细胞中诱导[Ca2+]I的提升，其EC50值为2.4 nM。
TP2242 [Des-octanoyl]-Ghrelin (rat)

Others Others
[Des-octanoyl]-Ghrelin (rat) is a Non-acylated, major circulating isoform of ghrelin.
TP2241 [Des-octanoyl]-Ghrelin (human)

Others Others
[Des-octanoyl]-Ghrelin (human) is a Non-acylated, major circulating isoform of ghrelin.
T76318 GHRF, porcine

GHRF, porcine 是一种生长激素释放激素 (GHRH) 多肽 (porcine)。GHRF, porcine 与 GHRHR 受体结合并促进生长激素的释放。
T76325 GHRF, bovine

GHRF, bovine (bGRF(1-44)-NH2) 是牛生长激素 (GH) 释放因子 (GHRF)。GHRF, bovine 促牛生长激素释放，并受到Hydrocortisone 的促进作用。
TP2032 des-​Gln14-​Ghrelin

des-Gln14-Ghrelin (rat)
An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH release in vivo.
T75157L Cimdelirsen sodium

Cimdelirsen (sodium) 为针对肝脏的反义寡核苷酸，通过减少生长激素受体(GHr)合成，抑制生长激素(GH)的过度分泌效应，进而降低肢端肥大症患者体内循环胰岛素样生长因子-1 (IGF-1)水平。
T75157 Cimdelirsen

Cimdelirsen为针对肝脏的反义寡核苷酸，通过降低生长激素受体(GHr)的合成量，来减少生长激素(GH)过量分泌所导致的不良影响，进而在肢端肥大症患者中降低循环胰岛素样生长因子-1(IGF-1)的水平。

化合物

[His1,Nle27] GHRF (1-32), amide, human
Cat.No: T76317
Synonym:
Target:
Ghrelin receptor full agonist-2
Cat.No: T40234
Synonym:
Target:
rGHRH(1-29)NH2
Cat.No: TP1393
Synonym:
Target:
GHRF, mouse
Cat.No: T82322
Synonym: Mouse growth hormone-releasing factor
Target:
des-​Gln14-​Ghrelin TFA
Cat.No: T75928
Synonym:
Target:
[Des-octanoyl]-Ghrelin (rat)
Cat.No: TP2242
Synonym:
Target: Others
[Des-octanoyl]-Ghrelin (human)
Cat.No: TP2241
Synonym:
Target: Others
GHRF, porcine
Cat.No: T76318
Synonym:
Target:
GHRF, bovine
Cat.No: T76325
Synonym:
Target:
des-​Gln14-​Ghrelin
Cat.No: TP2032
Synonym: des-Gln14-Ghrelin (rat)
Target:
Cimdelirsen sodium
Cat.No: T75157L
Synonym:
Target:
Cimdelirsen
Cat.No: T75157
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T80006 Emoghrelin

GHSR GPCR/G Protein
Emoghrelin是一种从Polygonum multiflorum（何首乌）提取的化合物，能够通过激活生长素释放肽受体来刺激生长激素的分泌。

天然产物

Emoghrelin
Cat.No: T80006
Synonym:
Target: GHSR
Species：
Human (4)
Mouse (4)
Rat (2)
Rabbit (1)
Rhesus (1)
Sus scrofa (Pig) (1)
Expression System：
HEK293 Cells (7)
E. coli (6)
Tag：
C-6xHis (2)
C-hFc (2)
His (2)
N-6xHis (2)
C-His (1)
His, hFc (1)
N-10xHis, C-Myc (1)
N-6xHis-GST (1)
N-hFc (1)
Cat. No. Product Name Species Expression System
TMPK-00806 GHR/Growth Hormone R Protein, Human, Recombinant (His)

GHR/BP,GH receptor,GHBP,GHR

 Human HEK293 Cells
Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
TMPY-01448 GHR/Growth Hormone R Protein, Mouse, Recombinant (His)

GHR/BP,growth hormone receptor,GHBP

 Mouse HEK293 Cells
GHR/Growth Hormone R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.3 kDa and the accession number is Q3UP14.
TMPY-00977 GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc)

growth hormone receptor,GHR/BP,GHBP

 Mouse HEK293 Cells
GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q3UP14.
TMPJ-00356 GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

GHBP,GHR,Somatotropin receptor,growth hormone recep...

 Mouse HEK293 Cells
Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway lead...
TMPH-03204 GHR Protein, Rabbit, Recombinant (His & Myc)

Rabbit E. coli
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P19941.
TMPH-03112 GHR Protein, Pig, Recombinant (His)

Sus scrofa (Pig) E. coli
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Pig, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is P19756.
TMPH-02440 GHR Protein, Rhesus macaque, Recombinant (His)

Rhesus E. coli
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rhesus macaque, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.2 kDa and the accession number is P79194.
TMPY-02007 GHR/Growth Hormone R Protein, Rat, Recombinant (His)

growth hormone receptor

 Rat HEK293 Cells
GHR/Growth Hormone R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is P16310-1.
TMPY-04281 GHR/Growth Hormone R Protein, Rat, Recombinant (hFc)

growth hormone receptor

 Rat HEK293 Cells
GHR/Growth Hormone R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.4 kDa and the accession number is P16310-1.
TMPH-02522 GHRL Protein, Mouse, Recombinant (His)

Mouse E. coli
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. GHRL Protein, Mouse, Recombinant (His) is expressed in E. coli expre...
TMPY-00186 GHRH Protein, Human, Recombinant (hFc)

GRF,INN,growth hormone releasing hormone,GHRF

 Human HEK293 Cells
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl...
TMPH-01087 CSH2 Protein, Human, Recombinant (GST & His)

Chorionic somatomammotropin hormone 2,Lactogen,Choriomammotr...

 Human E. coli
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. CSH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 53.8 kDa and the accession number is P0DML3.
TMPH-02274 JAK2 Protein, Human, Recombinant (His)

Human E. coli
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple int...

重组蛋白

GHR/Growth Hormone R Protein, Human, Recombinant (His)
Cat.No: TMPK-00806
Species: Human
Expression System: HEK293 Cells
GHR/Growth Hormone R Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01448
Species: Mouse
Expression System: HEK293 Cells
GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-00977
Species: Mouse
Expression System: HEK293 Cells
GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00356
Species: Mouse
Expression System: HEK293 Cells
GHR Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03204
Species: Rabbit
Expression System: E. coli
GHR Protein, Pig, Recombinant (His)
Cat.No: TMPH-03112
Species: Sus scrofa (Pig)
Expression System: E. coli
GHR Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPH-02440
Species: Rhesus
Expression System: E. coli
GHR/Growth Hormone R Protein, Rat, Recombinant (His)
Cat.No: TMPY-02007
Species: Rat
Expression System: HEK293 Cells
GHR/Growth Hormone R Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04281
Species: Rat
Expression System: HEK293 Cells
GHRL Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02522
Species: Mouse
Expression System: E. coli
GHRH Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00186
Species: Human
Expression System: HEK293 Cells
CSH2 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01087
Species: Human
Expression System: E. coli
JAK2 Protein, Human, Recombinant (His)
Cat.No: TMPH-02274
Species: Human
Expression System: E. coli
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