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Cat. No. | Product Name | Target | Signaling Pathways |
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T11393 |
GET73
Gamma hydroxybutyric acid analogue,GET 73 |
GluR | Neuroscience |
GET73 (Gamma hydroxybutyric acid analogue) 是天然神经递质 γ-羟基丁酸的类似物。它对谷氨酸在海马的传递有显著的影响。它具有抗酒精和抗焦虑的作用。 | |||
T24146 |
HOCPCA
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HOCPCA is an effective and selective ligand for the GHB binding sites that acts by binding with 27 times better affinity than GHB itself and crossing the blood-brain barrier in vitro and in vivo. | |||
T69259 |
NCS-356 sodium
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NCS-356 sodium is a GHB receptor agonist. | |||
T71533 |
NCS-356 sodium monohydrate
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NCS-356 sodium monohydrate is a GHB receptor agonist. | |||
T29058 |
UMB68 sodium
UMB-68 sodium,UMB68,UMB-68,UMB 68 |
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UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors. | |||
T23473 | trans-4-Hydroxycrotonic acid | Others | Others |
ligand of γ-hydroxybutyric acid (GHB) receptor | |||
T39962 |
Valiloxibic acid
XWL-008,Acidum valiloxibicum |
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Valiloxibic acid is a prodrug of γ-Hydroxybutyric acid (GHB).GHB is a naturally occurring neurotransmitter and a psychoactive drug, it acts on the GHB receptor and is a weak agonist at the GABAB receptor. | |||
T68181 |
NCS-356
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NCS-356 is a GHB receptor agonist. | |||
T37822 | AR-C 141990 hydrochloride | ||
Monocarboxylate transporter (MCT1) inhibitor (pKi = 7.6. Exhibits approximately 10-fold selectivity for MCT1 over MCT2 and no significant activity against MCT3 or 4. Inhibits graft versus host response and prolongs cardiac graft survival in a rat model. Immunosuppressant. Also inhibits brain penetration of GHB analog HOCPCA. |
Cat. No. | Product Name | Target | Signaling Pathways |
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T5273 |
2-Hydroxy-3-methylbutanoic acid
2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,2-羟基-3-甲基丁酸,(±)-2-Hydroxyisopentanoic Acid |
Others; Endogenous Metabolite | Metabolism; Others |
2-Hydroxy-3-methylbutanoic acid ((±)-2-Hydroxyisopentanoic Acid) 是一种 GHB 的结构类似物,其中GHB 是一种中枢神经系统中发现的天然物质,也是一种神经药物。 |