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Cat. No. Product Name Target Signaling Pathways
T11338 Furamidine

DB75,NSC 305831

Others Others
Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine (DB75) is abisbenzamidine derivative and an antiparasite agent. Furamidine is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine is effective both with single- and ...
T27395 Furamidine dihydrochloride

DB 75, DB75, NSC 305831, WR199385,Furamidine HCl

Furamidine is a cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1). Furamidine binds to strings of AT base pair sequences in DNA′s minor groove. Furamidine targets the enzyme active site and is primarily competitive with t
T16428 Pafuramidine

DB289

Others Others
Pafuramidine is an orally bioavailable prodrug of furamidine. It has activity against Pneumocystis pneumonia (IC50 value: 4.5 nM)
T24587 Pafuramidine maleate

DB-289,DB289,DB 289

Pafuramidine is an orally bioavailable prodrug of formamidine which was developed for the treatment of human African trypanosomiasis.
T64372 DB722

Others Others
DB722是一种具有DNA 结合活性的呋喃脒类似物。DB722显示抗增殖活性。

化合物

Furamidine
Cat.No: T11338
Synonym: DB75,NSC 305831
Target: Others
Furamidine dihydrochloride
Cat.No: T27395
Synonym: DB 75, DB75, NSC 305831, WR199385,Furamidine HCl
Target:
Pafuramidine
Cat.No: T16428
Synonym: DB289
Target: Others
Pafuramidine maleate
Cat.No: T24587
Synonym: DB-289,DB289,DB 289
Target:
DB722
Cat.No: T64372
Synonym:
Target: Others
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