Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T61354 |
Fosphenytoin
|
Others | Others |
Fosphenytoin 是一种磷酸酯前药,可替代静脉注射苯妥英,用于急性干预癫痫发作。Fosphenytoin 在肠胃外给药可水解成具有抗惊厥作用的苯妥英。Fosphenytoin 可用于多种给药方式,如静脉注射和腹腔注射。 | |||
T7066 |
Fosphenytoin disodium
Fosphenytoin sodium,ACC-9653,磷苯妥英钠 |
Sodium Channel | Membrane transporter/Ion channel |
Fosphenytoin disodium (ACC-9653) 是 phenytoin 的前体药物,具有抗惊厥等活性。它是电压门控钠通道阻滞剂。 | |||
T68918 |
Phenytoin-d10
|
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Phenytoin-d10 is intended for use as an internal standard for the quantification of phenytoin by GC- or LC-MS. Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin. Phenytoin is formed from fosphenytoin by tissue phosphatases. It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner. Phenytoin reduces the neuronal firing frequency and decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat corticostriatal... |