Cat. No. | Product Name | Target | Signaling Pathways |
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T69758 |
Flutamide-d7
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Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft mo... | |||
T69757 |
PDDC inhibitor
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HIV Protease | Microbiology/Virology; Proteases/Proteasome |
PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) 是一种具有选择性和高效性的 nSMase2 抑制剂 ,可用于研究 HIV 感染。 |