Cat. No. | Product Name | Target | Signaling Pathways |
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T24438 |
MDK5466
MDK-5466,MDK 5466,E21,Flt3-IN-III,Flt3 Inhibitor III |
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MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death. | |||
T71400 |
Quizartinib HCl
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Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro... |