Cat. No. | Product Name | Target | Signaling Pathways |
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T16711 | Flesinoxan | 5-HT Receptor | GPCR/G Protein; Neuroscience |
Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM). | |||
T68194 |
Flesinoxan HCl
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Flesinoxan HCl is the salt form of Flesinoxan, which is a selective 5-HT1A receptor agonist. | |||
T70183 |
Eptapirone fumarate
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Eptapirone, also known as F11440, is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone, in exerting 5-HT1A agonist activity at pre- and postsynaptic receptors in rats (measured by, for exam... |