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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T81968 |
KY-1044
SAR 445256,Alomfilimab |
||
KY-1044 (Alomfilimab; SAR 445256) 是一种全人IgG1抗体,针对诱导型共刺激受体(ICOS)。该化合物借助FcgRIIIa作用,通过抗体依赖性细胞毒性(ADCC)清除高表达ICOS的细胞,并在低表达ICOS的CD8+TEff细胞上通过FcgR依赖的聚集发挥共刺激作用。通过操纵T细胞亚型上ICOS的异质性表达,KY-1044旨在优化肿瘤微环境,并恢复对肿瘤的免疫应答。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00791 |
Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi)
FCG3,IGFR3,FcgRIIIA,FCGR3,Fc γ RIIIA,FCGR3A,CD16,Fc... |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is P08637-1. | |||
TMPK-00599 |
Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)
FCGR3,IGFR3,FcR-10,Fc γ RIIIA/CD16a (V176) Domain 2 Protein,... |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 35.29 kDa and the accession number is AAH17865. | |||
TMPK-00597 |
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi)
CD16,FcRIII,IMD20,IGFR3,FCG3,Fc γ RIIIA,CD16A,FCGR3,FcRIIIa,... |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is AAH17865. | |||
TMPK-00598 |
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated
Fc gamma RIIIA,Fc γ RIIIA,FCGR3,FcRIII,FCG3,IGFR3,FCGR3A,FcR... |
Human | HEK293 Cells |
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. | |||
TMPK-00792 |
Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated
FCGR3A,FcRIII,FCGR3,Fc γ RIIIA,CD16A,FcgRIIIA,IGFR3... |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is P08637-1. |