Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11308 |
FM26
|
ROR | Metabolism |
FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM. |