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Cat. No. Product Name Target Signaling Pathways
T40031 Thalidomide-O-C6-NH2 hydrochloride

4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐

E3 Ligase Ligand-Linker Conjugate PROTAC
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) 是一种合成的E3 连接酶配体 -linker 偶联物,用于 PROTAC dTAG-13 的合成。其中 dTAG-13 是一种 FKBP12F36V 和 BET 的降解剂。
T40251 dTAGV-1 TFA

dTAGV-1 TFA is a highly effective and specific compound that targets mutant FKBP12 F36V fusion proteins for degradation. It possesses potent activity in inducing the degradation of the FKBP12 F36V -Nluc protein in living organisms.
T13549 AP1867-3-(aminoethoxy)

Others Others
AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader.
T74556 dTAG-47

dTAG-47,异双功能 dTAG 分子,靶向突变型 FKBP12 (FKBP12F36V)。FKBP12F36V 可用作降解标签 (dTAG) 并与靶蛋白融合。dTAG-47可用于基底样乳腺癌(BBC)的研究。
T74412 dTAGV-1-NEG TFA

dTAGV-1-NEG TFA 是一种非对映异构体,是 dTAGV-1 的异双功能阴性对照。dTAGV-1-NEG TFA 是一种 FKBP12F36V 选择性降解剂。
T36253 dTAGV-1

Degrader targeting mutant FKBP12F36V fusion proteins. Comprises a ligand selective for F36V single-point mutated FKBP12, a linker and a von Hippel-Lindau (VHL)-binding ligand. Induces potent and selective degradation of FKBP12F36V fusion proteins in vitro and in vivo. Selectively degrades FKBP12F36V-EWS/FLI fusion proteins and inhibits cell proliferation in FKBP12F36V-EWS/FLI-expressing Ewing sarcoma cells. Hydrochloride salt (Cat.No. 7374) available; suitable for in vivo use. Negative control...

化合物

Thalidomide-O-C6-NH2 hydrochloride
Cat.No: T40031
Synonym: 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐
Target: E3 Ligase Ligand-Linker Conjugate
dTAGV-1 TFA
Cat.No: T40251
Synonym:
Target:
AP1867-3-(aminoethoxy)
Cat.No: T13549
Synonym:
Target: Others
dTAG-47
Cat.No: T74556
Synonym:
Target:
dTAGV-1-NEG TFA
Cat.No: T74412
Synonym:
Target:
dTAGV-1
Cat.No: T36253
Synonym:
Target:
TargetMol Loading
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