Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03385 |
FKBP14 Protein, Human, Recombinant (His)
IPBP12,EDSKMH,FK506 binding protein 14, 22 kDa,... |
Human | HEK293 Cells |
FKBP14 belongs to the FK506-binding protein family. It contains 2 EF-hand domains and one PPIase FKBP-type domain. FKBP14 can be detected in the lumen of the endoplasmic reticulum where it is thought to accelerate the folding of proteins during protein synthesis. Truncation of the amino-terminus of FKBP14 significantly decreases peptidyl prolyl cis-trans isomerase activity, therefore implicating that the PPIase FKBP-type domain must be located at the N-terminus. Defects in FKBP14 can cause Ehler... |