Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11292 |
FKBP12 PROTAC dTAG-7
dTAG-7 |
Epigenetic Reader Domain | Chromatin/Epigenetic |
FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by connecting BET bromodomains to the E3 ubiquitin ligase CRBN. Additionally, it serves as a degrader of FKBP12F36V when FKBP12F36V is expressed in-frame with a targeted protein. |