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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9901A-001 |
Relatlimab
BMS-986016 |
Others | Others |
Relatlimab(BMS-986016) 是一种靶向人抗 LAG-3 的单克隆抗体,由携带重组 LAG-3 蛋白的人免疫球蛋白的转基因小鼠免疫生成。Relatlimb 有阻断作用,可阻断 LAG-3/MHC II 的相互作用(IC50 : 0.67 nM),阻断了 LAG-3/FGL1 的相互作用( IC50:0.019 nM)。Relatlimab 常与 Nivoluma 一起用来治疗晚期黑色素瘤。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05372 |
FGL1 Protein, Human, Recombinant (His)
LFIRE-1,LFIRE1,HFREP1,HP-041<... |
Human | Baculovirus Insect Cells |
FGL1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number is Q08830. | |||
TMPJ-00195 |
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
LFIRE-1,FGL1,Fibrinogen-like prot... |
Cynomolgus | HEK293 Cells |
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 36 KDa and the accession number is A0A2K5X990. | |||
TMPJ-00198 |
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
HFREP-1,HP-041,Fibrinogen-like protein |
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is Q08830. | |||
TMPJ-00197 |
FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
FGL1,HP-041,Fibrinogen-like prote... |
Human | HEK293 Cells |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major imm... | |||
TMPK-00204 |
FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
Hepassocin,Lag3 ligand,HP-041,LFIRE-1,HFRE... |
Human | HEK293 Cells |
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3. | |||
TMPY-05843 |
FGL1 Protein, Cynomolgus, Recombinant (hFc)
fibrinogen-like 1 |
Cynomolgus | HEK293 Cells |
FGL1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.94 kDa and the accession number is XP_005562748.1. | |||
TMPY-05734 |
FGL1 Protein, Human, Recombinant (hFc)
HFREP1,LFIRE1,LFIRE-1,fibrinogen-... |
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.7 kDa and the accession number is Q08830. | |||
TMPY-05450 |
FGL1 Protein, Mouse, Recombinant (His)
fibrinogen-like 1,Mfire1 |
Mouse | Baculovirus Insect Cells |
FGL1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number is A0A0R4J0E1. | |||
TMPY-05464 |
FGL1 Protein, Human, Recombinant (mFc)
HP-041,LFIRE-1,HFREP1,fibrinogen-... |
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q08830. | |||
TMPY-05844 |
FGL1 Protein, Cynomolgus, Recombinant (His)
fibrinogen-like 1 |
Cynomolgus | Baculovirus Insect Cells |
FGL1 Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.40 kDa and the accession number is XP_005562748.1. | |||
TMPY-05785 |
FGL1 Protein, Mouse, Recombinant (hFc)
fibrinogen-like 1,Mfire1 |
Mouse | HEK293 Cells |
FGL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.74 kDa and the accession number is A0A0R4J0E1. | |||
TMPY-05735 |
FGL1 Protein, Rat, Recombinant (His)
fibrinogen-like 1 |
Rat | Baculovirus Insect Cells |
FGL1 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.48 kDa and the accession number is Q5M8C6.1. | |||
TMPY-05778 |
FGL1 Protein, Human, Recombinant (His & Avi)
HFREP1,LFIRE1,LFIRE-1,HP-041<... |
Human | Baculovirus Insect Cells |
FGL1 Protein, Human, Recombinant (His & Avi) is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 37.27 kDa and the accession number is Q08830. |