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Search Results for " fgf19 "
Targets Recommended: FGFR

2

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T7738 H3B-6527

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
H3B-6527 是一种在 FGF19 驱动的肝细胞癌中有效且选择性的 FGFR4 抑制剂,具有抗肿瘤活性。
T63704 FGFR4-IN-11

FGFR4-IN-11 是选择性的、有效的、共价结合的 FGFR4 抑制剂 (IC50: 2.1 nM)。FGFR4-IN-11 能够明显抑制 FGF19/FGFR4 信号通路,表现出抗癌效果。

化合物

H3B-6527
Cat.No: T7738
Synonym:
Target: FGFR
FGFR4-IN-11
Cat.No: T63704
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02907 FGF-19 Protein, Human, Recombinant

fibroblast growth factor 19,FGF19

Human E. coli
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca...
TMPJ-00715 FGF-19 Protein, Human, Recombinant (His)

FGF-19,Fibroblast growth factor 19

Human E. coli
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ...

重组蛋白

FGF-19 Protein, Human, Recombinant
Cat.No: TMPY-02907
Species: Human
Expression System: E. coli
FGF-19 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00715
Species: Human
Expression System: E. coli
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