Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77586 |
Eg5-IN-1
|
Kinesin | Cytoskeletal Signaling |
Eg5-IN-1 是一种有效的驱动蛋白家族运动蛋白 (Eg5) 抑制剂,对 Eg5 的 IC50 值为 1.97 µM。Eg5-IN-1 可用于研究癌症。 | |||
T11155 |
Eg5 Inhibitor V, trans-24
|
Kinesin | Cytoskeletal Signaling |
Eg5 Inhibitor V, trans-24 是一种有效的、特异性的驱动蛋白 Eg5 抑制剂,IC50 值为 0.65 μM,可用于癌症的研究。 | |||
T6393 |
ARQ 621
|
Kinesin | Cytoskeletal Signaling |
ARQ 621 是一种变构和选择性 Eg5 有丝分裂运动蛋白抑制剂,具有抗肿瘤活性。 | |||
T36816 |
S-trityl-L-Cysteine
STLC |
Kinesin | Cytoskeletal Signaling |
S-Trityl-L-cysteine 是别构驱动蛋白Eg5的选择性抑制剂。rityl-L-cysteine 抑制基础 ATPase 活性的IC50为 1 μM,抑制微管激活的 ATPase 活性的IC50为 140 nM。S-Trityl-L-cysteine 显示出抗肿瘤活性。 | |||
T18295 |
Mal-PEG5-Boc
Mal-PEG5-COOtBu,Mal-PEG5-T-Butyl Ester |
Others; PROTAC Linker | Others; PROTAC |
Mal-PEG5-Boc (Mal-PEG5-COOtBu) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17515 |
Azido-PEG5-azide
叠氮-五聚乙二醇-叠氮 |
Others; PROTAC Linker | Others; PROTAC |
Azido-PEG5-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16218 | N-Boc-PEG5-bromide | Others; PROTAC Linker | Others; PROTAC |
N-Boc-PEG5-bromide 是 PROTAC 的 linker,属于 PEG 类和 Alkyl/ether 类.它也是可降解的 ADC 连接桥,用于抗体药物结合物的合成。 | |||
T15534 |
Hydroxy-PEG5-Boc
1-羟基-3,6,9,12,15-五氧杂十八烷-18-羧酸叔丁酯 |
PROTAC Linker | PROTAC |
Hydroxy-PEG6-Boc 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17352 |
Acid-C1-PEG5-Boc
|
Others; PROTAC Linker | Others; PROTAC |
Acid-C1-PEG5-Boc 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17724 | Cbz-NH-PEG5-CH2COOH | Others; PROTAC Linker | Others; PROTAC |
Cbz-NH-PEG5-CH2COOH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18588 |
Propargyl-PEG5-Ms
Propargyl-PEG6-Ms |
Others; PROTAC Linker | Others; PROTAC |
Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T14838 | Butoxycarbonyl-PEG5-sulfonic acid | Others | Others |
Butoxycarbonyl-PEG5-sulfonic acid is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1]. | |||
T15535 | Hydroxy-PEG5-C2-methyl ester | Others | Others |
Hydroxy-PEG5-C2-methyl ester is a polyethylene glycol (PEG) derived linker compound employed in PROTAC (PROteolysis TArgeting Chimeras) synthesis[1]. | |||
T15065 | DBCO-NHCO-PEG5-NHS ester | Others | Others |
DBCO-NHCO-PEG5-NHS ester is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1]. | |||
T14809 | Bromo-PEG5-phosphonic acid diethyl ester | Others | Others |
Bromo-PEG5-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker for PROTAC synthesis[1]. It is utilized in the construction of PROteolysis TArgeting Chimeras (PROTACs), which are heterobifunctional molecules designed to induce protein degradation. | |||
T17436 | Amino-PEG6-amido-bis-PEG5-N3 | Others | Others |
Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11-unit polyethylene glycol (PEG) linker that finds application in the synthesis of antibody-drug conjugates (ADCs) [1]. | |||
T18742 | t-Boc-Aminooxy-PEG5-azide | Others | Others |
t-Boc-Aminooxy-PEG5-azide is a polyethylene glycol (PEG) derivative that serves as a linker for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T18337 | Methyltetrazine-amido-PEG5-alkyne | Others | Others |
Methyltetrazine-amido-PEG5-alkyne is a polyethylene glycol (PEG) derivative commonly employed as a linker for proteolysis targeting chimeras (PROTACs) synthesis [1]. | |||
T16636 | Propargyl-PEG5-amine | Others | Others |
Propargyl-PEG5-amine is a non-cleavable linker compound, employed in the synthesis of antibody-drug conjugates (ADCs) and PROTACs. It is PEG-based and serves as a connector in the formation of ADCs and PROTACs[1]. | |||
T17517 | Azido-PEG5-triethoxysilane | Others | Others |
Azido-PEG5-triethoxysilane serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1]. | |||
T17996 |
VH032-PEG5-C6-Cl
HaloPROTAC 2 |
Others | Others |
VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule HaloPROTAC that incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1]. | |||
T74438 | β-Glucuronide-dPBD-PEG5-NH2 TFA | ||
β-Glucuronide-dPBD-PEG5-NH2 TFA 是一种通过β-葡糖苷酸与pyrrolobenzodiazepine形成的二聚体,能够与异戊二烯化的抗体结合,生成抗体-活性分子偶联物(ADC) cIRCR201-dPBD。该化合物中的β-葡糖苷酸键作为可降解的ADC Linker,有助于减少副作用。β-Glucuronide-dPBD-PEG5-NH2 TFA 作为cIRCR201-dPBD的前体,显示出能诱导细胞凋亡(apoptosis)和阻滞细胞周期,具备抗肿瘤活性。 | |||
T18646 |
Pyrene-PEG5-biotin
|
Others | Others |
Pyrene-PEG5-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T15899 |
m-PEG5-phosphonic acid
|
Others | Others |
m-PEG5-phosphonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14108 |
Acid-PEG5-C2-Boc
|
Others | Others |
Acid-PEG5-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T40597 |
Chloro-PEG5-chloride
Chloro-PEG5-chloride |
||
Chloro-PEG5-chloride is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T17804 |
DBCO-PEG5-DBCO
|
Others | Others |
DBCO-PEG5-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18026 |
HS-PEG5-CH2CH2NH2
Thiol-PEG5-amine |
Others | Others |
HS-PEG5-CH2CH2NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T15891 |
m-PEG5-Br
|
Others | Others |
m-PEG5-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18775 |
TCO-PEG5-maleimide
|
Others | Others |
TCO-PEG5-maleimide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T39462 |
Nonylbenzene-PEG5-OH
Nonylbenzene-PEG5-OH |
||
Nonylbenzene-PEG5-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T17865 |
DSPE-PEG5-azide
|
Others | Others |
DSPE-PEG5-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T38702 |
Thiol-C9-PEG5
Thiol-C9-PEG5 |
||
Thiol-C9-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14732 |
Boc-N-PEG5-C2-NHS ester
|
Others | Others |
Boc-N-PEG5-C2-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T16462 |
PEG5-Tos
|
Others | Others |
PEG5-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14604 |
Biotin-PEG5-azide
|
Others | Others |
Biotin-PEG5-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14457 |
Azido-PEG5-amine
|
Others | Others |
Azido-PEG5-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14701 |
BnO-PEG5-OH
|
Others | Others |
BnO-PEG5-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T38745 |
Bis-methacrylate-PEG5
Bis-methacrylate-PEG5 |
||
Bis-methacrylate-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T38690 |
Benzyl-PEG5-Ots
Benzyl-PEG5-Ots |
||
Benzyl-PEG5-Ots is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T38689 |
Propargyl-PEG5-Br
Propargyl-PEG5-Br |
||
Propargyl-PEG5-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14806 |
Bromo-PEG5-Boc
|
Others | Others |
Bromo-PEG5-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18025 |
HS-PEG5-CH2CH2N3
|
Others | Others |
HS-PEG5-CH2CH2N3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T39464 |
Benzyl-PEG5-NHBoc
Benzyl-PEG5-NHBoc |
||
Benzyl-PEG5-NHBoc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T16209 |
N-Boc-N-bis-PEG5
|
Others | Others |
N-Boc-N-bis-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T15890 |
m-PEG5-Boc
|
Others | Others |
m-PEG5-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T83953 |
Pomalidomide 4'-PEG5-amine
|
||
Pomalidomide 4'-PEG5-amine是一种功能化的cereblon配体,用于PROTAC研究与开发;它结合了一个E3连接酶配体和一个末端带有氨基的PEG5连接体,以便与目标蛋白配体进行共轭。它是专为PROTAC研发设计的一系列功能化工具分子之一。 | |||
T18872 |
(S,R,S)-AHPC-PEG5-COOH
VH032-PEG5-COOH,E3 Ligase Ligand-Linker Conjugates 58,VHL Ligand-Linker Conjugates 16 |
Others | Others |
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1]. | |||
T14826 |
Bromoacetamido-PEG5-azide
|
Others | Others |
Bromoacetamido-PEG5-azide is a polyethylene glycol (PEG)-based linking molecule, commonly known as a PROTAC linker, which is utilized for the efficient synthesis of PROTACs[1]. | |||
T16059 |
Methyltetrazine-PEG5-alkyne
|
Others | Others |
Methyltetrazine-PEG5-alkyne, a PEG-based PROTAC linker, is utilized in synthesizing PROTACs[1]. |