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Cat. No.	Product Name	Target	Signaling Pathways
T2368L	Edoxaban Lixiana,依杜沙班	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Edoxaban (Lixiana) (DU-176) 是一种选择性的，口服有效的 factor Xa (FXa)抑制剂。Edoxaban 对游离 FXa 和凝血酶原的 Ki 分别为 0.561 nM 和 2.98 nM。Edoxaban 是一种抗凝剂，可用于预防中风。Edoxaban 还是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂，Ki 值分别为 6.00 μM 和 41.7 μM，对 FXa 的选择性超过 10000 倍。由于具有抗血栓形成的特性，Edoxaban 可用于预防血栓栓塞性疾病的研究。
T2368	Edoxaban Tosylate Monohydrate DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban,依度沙班对甲苯磺酸盐一水化合物	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Edoxaban Tosylate Monohydrate (DU-176b tosylate Monohydrate) 是口服具有活力的 factor Xa 选择性抑制剂。它是一种抗凝剂，可用于预防中风，是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂，对 FXa 的选择性超过 10000 倍。它具有抗血栓形成的特性，可用于血栓栓塞性疾病的研究。
T41316	Edoxaban tosylate

T19873	Edoxaban M4 D21-2393,D21 2393,UNII-IV344R972X,Edoxaban 4-Carboxylic Acid
	D21-2393 subjects received a single-oral-dose of edoxaban 30-90 mg in each study occasion under fasting condition. Serial blood samples were collected to measure the plasma concentrations of edoxaban and its major active metabolite D21-2393. Meanwhile, PT, INR, aPTT were measured pre- and post-dose.
T37175	Edoxaban impurity 4
	Edoxaban impurity 4, an impurity of Edoxaban (DU-176), is a selective, potent, and orally active inhibitor of factor Xa (FXa), exhibiting Kis of 0.561 nM for free FXa and 2.98 nM for prothrombinase. As an anticoagulant agent, Edoxaban is utilized for stroke prevention[1][2].
T37176	Edoxaban impurity 6
	Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2]. [1]. Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9.[2]. Mendell J, Lee F, Chen S, The Effe...
T21037	Edoxaban Isomer
	Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.
T64126	Edoxaban hydrochloride
	Edoxaban (DU-176b) hydrochloride 是一种高效的、选择性的、口服具有活力的、直接的Factor Xa (FXa) 抑制剂，能够作用于人游离 FXa (Ki: 0.561 nM) 和凝血酶原酶 (Ki: 2.98 nM)。Edoxaban hydrochloride 的选择性是其他凝血蛋白酶的 10000 倍以上。Edoxaban hydrochloride 能够用于研究预防血栓栓塞性疾病。