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Cat. No.	Product Name	Target	Signaling Pathways
T2335	Ebastine Ebastel,依巴斯汀,LAS-W 090,Ebastin,Kestine,RP64305	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Ebastine (Kestine) 是一种可口服的组胺 H1 受体拮抗剂，用于过敏性鼻炎的症状和慢性特发性荨麻疹的研究。
T37515	Hydroxy Ebastine
	Hydroxy Ebastine is an ebastine metabolite. Ebastine undergoes rapid first-pass metabolism by the cytochrome P450 isoform CYP2J2 to form hydroxy ebastine which is then metabolized by CYP2J2 and CYP3A4 to form carebastine.
T10680	Carebastine	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Carebastine 是 Ebastine 的活性代谢产物，可抑制巨噬细胞移动抑制因子的表达。它是组胺 H1 受体拮抗剂，可抑制 VEGF 诱导的 HUVEC 和 HPAEC 增殖，迁移和血管生成。