Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4061 |
LY2334737
|
Nucleoside Antimetabolite/Analog; Others; Virus Protease | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
LY2334737 是一种具有口服活性的 Gemcitabine 的前药,也是核苷类似物。它抑制肠道病毒 A71 感染,有抗病毒和抗癌活性。 | |||
T61462 |
EV-A71-IN-1
|
||
EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 μM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP1 protein and the host receptor hSCARB2. It displays broad-spectrum antiviral activity against various human enteroviruses, while being non-toxic to human cells (CC50 > 56.2 μM) [1]. | |||
T74487 | AL-470 | ||
AL-470 是一个有效的抗病毒剂,对HIV-1、HIV-2、EV-A71的EC50值分别为0.27、0.63 和 0.35 µM。 | |||
T60880 | Viral 2C protein inhibitor 1 | ||
Viral 2C protein inhibitor 1 (compound 6aw) 是广谱抗肠病毒剂,可抑制病毒 2C 蛋白。Viral 2C protein inhibitor 1 具有相对较低的细胞毒性和较高的选择性指数。Viral 2C protein inhibitor 1 可抑制 EV-D68、EV-A71 和 CVB3 等多种菌株,EC50值为 0.1~3.6 μM。 |