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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82858 |
Bleselumab
ASKP 1240,Anti-Human CD40 Recombinant Antibody |
||
Bleselumab (ASKP 1240)为人源化抗-CD40单克隆抗体,通过高亲和力(Kd: 0.24 nM)与CD40结合,阻断CD40与CD40L配体的相互作用,从而抑制免疫反应,用于预防器官移植排斥。 | |||
T62846 | Freselestat quarterhydrate | ||
Freselestat quarterhydrate (ONO-6818 quarterhydrate) 是一种有效的、口服具有活力的嗜中性粒细胞弹性蛋白酶 (neutrophil elastase) 抑制剂 (Ki: 12.2 nM)。Freselestat quarterhydrate 对其他蛋白酶(例如胰蛋白酶,蛋白酶3,胰弹性蛋白酶,凝血酶,纤溶酶,胶原酶,组织蛋白酶G 和鼠巨噬细胞弹性蛋白酶)的活性低 100 倍以上,表现出有效的抗炎作用。 | |||
T29070 |
Uproleselan
|
||
Uproleselan has antithrombotic and antineoplastic properties. | |||
T31877 |
Freselestat
ONO-PO 736,ONO-6818,ONO 6818,ONO6818 |
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Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass. | |||
T125065 |
5-Hydroxyseselin
|
||
5-Hydroxyseselin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125065。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN5891 |
Seselin
|
Antiviral; Immunology/Inflammation related | Immunology/Inflammation |
Seselin 是来自 Plumbago zeylanica 的天然产品。 Seselin 具有抗炎和抗病毒活性。 | |||
TN1587 |
Dihydroseselin
ZINC302323,8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one,二氢邪蒿内酯 |
Others | Others |
Dihydroseselin (8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one) 是一种源自 Toddalia 根的香豆素。 | |||
T35000 |
Uproleselan sodium
GMI 1271,GMI1271,GMI-1271 |
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Uproleselan sodium (GGI-1271) is a small molecule E-selector antagonist originally targeted at AML as an adjuvant to standard chemotherapy for hematological malignancies. | |||
TN5892 |
5-Methoxyseselin
|
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5-Methoxyseselin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5892,CAS号为 31525-76-5。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01167 |
E-Selectin/CD62E Protein, Human, Recombinant (His)
ELAM,selectin E,CD62E,ELAM1,LECAM2,ESEL |
Human | HEK293 Cells |
E-Selectin/CD62E Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.1 kDa and the accession number is P16581. | |||
TMPY-05488 |
E-Selectin/CD62E Protein, Human, Recombinant (hFc)
CD62E,ESEL,ELAM1,ELAM,selectin E,LECAM2 |
Human | HEK293 Cells |
E-Selectin/CD62E Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.4 kDa and the accession number is P16581. | |||
TMPK-00487 |
E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa 22-554, His)
selectin E,ELAM,ESEL,SELE,E-Selectin,LECAM2,CD62E,E... |
Cynomolgus | HEK293 Cells |
E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa 22-554, His) is expressed... | |||
TMPK-00349 |
E-Selectin/CD62E Protein, Human, Recombinant (His & Avi)
ESEL,RP1-117P20.2,CD62E,ELAM,ELAM1,selectin E,E-Sel... |
Human | HEK293 Cells |
E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. E-Selectin/CD62E Protein, Human, Recombinant (His & Avi) is expressed in HEK293... | |||
TMPK-00350 |
E-Selectin/CD62E Protein, Human, Recombinant (His & Avi), Biotinylated
CD62E,ELAM,SELE,selectin E,LECAM2,ESEL,RP1-117P20.2... |
Human | HEK293 Cells |
E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. E-Selectin/CD62E Protein, Human, Recombinant (His & Avi), Biotinylated is expre... |