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Targets Recommended: Dopamine Receptor

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9409	Mesdopetam hemitartrate IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Mesdopetam hemitartrate (IRL790 hemitartrate) 是一种多巴胺D3受体拮抗剂 (Ki=90 nM;IC50=9.8 μM)，具有稳定精神运动的作用，可用于帕金森病的运动和精神并发症的研究。
T72282	Ebaresdax hydrochloride	Endogenous Metabolite	Metabolism
	Ebaresdax hydrochloride 具有镇痛活性，,可用于研究由I型或II型糖尿病引起的糖尿病性神经病变疼痛。
T38828	Mesdopetam IRL790
	Mesdopetam (IRL790) is a dopamine D3 receptor antagonist with a Ki of 90 nM and an IC50 of 9.8 μM for the human recombinant D3 receptor. It exhibits psychomotor stabilizing properties and is utilized in the study of motor and psychiatric complications associated with Parkinson's disease.
T63818	Omesdafexor
	Omesdafexor 是 FXR 激动剂，能够用于研究肝病或代谢性炎症引起的疾病。
T35410	(+)-Goniothalesdiol
	(+)-Goniothalesdiol, isolated from the bark of the Malaysian tree G. borneensis, is a tetrahydrofuran compound known to have significant cytotoxic effects against P388 mouse leukemia cells and pesticidal activities. It has been shown to have promising cytotoxic activity against p388 mouse leukemia cells (ED50 ≥30 μg/ml).

化合物

Mesdopetam hemitartrate

Cat.No: T9409

Synonym: IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)

Target: Dopamine Receptor

Ebaresdax hydrochloride

Cat.No: T72282

Synonym:

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03391	ESD Protein, Human, Recombinant (His) esterase D,FGH	Human	E. coli
	Esterase D, also known as ESD, is a serine hydrolase that belongs to the esterase D family. Esterase D is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. Esterase D gene is used as a genetic marker and a diagnostic tool for retinoblastoma, Wilson's disease and other hereditary or acquired diseases controlled by genes located at the 13 chromosome 13q14 region.
TMPJ-00459	Esterase D Protein, Human, Recombinant (His) FGH,Methylumbelliferyl-Acetate Deacetylase,ESD,S-Fo...	Human	E. coli
	Human Esterase D is a cytoplasmic serine hydrolase that belongs to the esterase D family. Esterase D is involved in the detoxification of formaldehyde. Esterase D plays a part in a variety of substrates, including O-acetylated sialic acids, which may involves in the recycling of sialic acids. Esterase D is used as a genetic marker for retinoblastoma and Wilson’s disease.
TMPY-01451	MESDC2 Protein, Human, Recombinant (His) MESD,mesoderm development candidate 2,BOCA	Human	HEK293 Cells
	MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside...