Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6853 |
GSK591
GSK3203591,EPZ015866 |
Histone Methyltransferase | Chromatin/Epigenetic |
GSK591 (GSK3203591) 是一种有效的精氨酸甲基转移酶 PRMT5 选择性抑制剂,IC50值为 11 nM。 | |||
T36981 |
GSK 591 dihydrochloride
|
||
Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website. |