2
3
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21762 |
LDN-211904
|
||
LDN-211904 oxalate (compound 32) 是一种有效的选择性EphB3抑制剂,IC50为 0.079 μM。LDN-211904 oxalate 在小鼠肝微粒体中具有良好的代谢稳定性。LDN-211904 oxalate 与西妥昔单抗联用可有效抑制 STAT3 激活的 CSC 干性和 CRC 中的西妥昔单抗耐药性。 | |||
T73368 |
UniPR505
|
Ephrin Receptor | Tyrosine Kinase/Adaptors |
UniPR505 是一种有效的 EphA2 拮抗剂(IC50:0.95 µM),是一种具有抗血管生成作用的新型 3α-氨基甲酰氧基衍生物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00898 |
EphB3 Protein, Human, Recombinant (His)
EC 2.7.10.1,EPHB3,ETK2,EK2,HEK2,AW456895,S... |
Human | HEK293 Cells |
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC. | |||
TMPY-01784 |
EphB3 Protein, Mouse, Recombinant (His)
MDK5,Tyro6,Etk2,HEK2,EPH receptor B3,Cek10,Sek4,AW4... |
Mouse | HEK293 Cells |
EphB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P54754. | |||
TMPY-00042 |
EphB3 Protein, Rat, Recombinant (His)
EPH receptor B3 |
Rat | HEK293 Cells |
EphB3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is A6JS76. |