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抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T21762 LDN-211904

LDN-211904 oxalate (compound 32) 是一种有效的选择性EphB3抑制剂,IC50为 0.079 μM。LDN-211904 oxalate 在小鼠肝微粒体中具有良好的代谢稳定性。LDN-211904 oxalate 与西妥昔单抗联用可有效抑制 STAT3 激活的 CSC 干性和 CRC 中的西妥昔单抗耐药性。
T73368 UniPR505

Ephrin Receptor Tyrosine Kinase/Adaptors
UniPR505 是一种有效的 EphA2 拮抗剂(IC50:0.95 µM),是一种具有抗血管生成作用的新型 3α-氨基甲酰氧基衍生物。

化合物

LDN-211904
Cat.No: T21762
Synonym:
Target:
UniPR505
Cat.No: T73368
Synonym:
Target: Ephrin Receptor
Cat. No. Product Name Species Expression System
TMPK-00898 EphB3 Protein, Human, Recombinant (His)

EC 2.7.10.1,EPHB3,ETK2,EK2,HEK2,AW456895,S...

Human HEK293 Cells
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.
TMPY-01784 EphB3 Protein, Mouse, Recombinant (His)

MDK5,Tyro6,Etk2,HEK2,EPH receptor B3,Cek10,Sek4,AW4...

Mouse HEK293 Cells
EphB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P54754.
TMPY-00042 EphB3 Protein, Rat, Recombinant (His)

EPH receptor B3

Rat HEK293 Cells
EphB3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is A6JS76.

重组蛋白

EphB3 Protein, Human, Recombinant (His)
Cat.No: TMPK-00898
Species: Human
Expression System: HEK293 Cells
EphB3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01784
Species: Mouse
Expression System: HEK293 Cells
EphB3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-00042
Species: Rat
Expression System: HEK293 Cells
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