Cat. No. | Product Name | Target | Signaling Pathways |
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T41150 |
EMD 527040 hydrochloride
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EMD 527040 hydrochloride 是一种有效的整合素α V β 6抑制剂。EMD 527040 hydrochloride 对α V β 6与纤维连接蛋白的结合和表达α V β 6的细胞与纤维连接蛋白的附着有抑制作用,IC 50值分别为6 nM 和1.6 μM。EMD 527040 hydrochloride 在胆道纤维化动物模型中显示出抗纤维化活性,并在体内具有活性。 | |||
T40943 |
EMD527040
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EMD527040 is a powerful and highly specific αvβ6 antagonist, exhibiting notable antifibrotic properties. It is suitable for conducting research on carcinoma and liver fibrosis. |