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4

抑制剂 & 化合物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T37455 C18 D-threo Ceramide (d18:1/18:0)

C18 D-threo Ceramide (d18:1/18:0)

C18 D-threoCeramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2[Matreya, LLC. Catalog No. 1855] 1.Koolath, S., Murai, Y., Suga, Y., et al.Chiral combinatorial preparation and biological evaluation of unique ceramides for inhibition of sphingomyelin synthaseChirality32(3)308-313(2019) 2.Usta, J., El Bawab, S., Roddy, P., et al.Structural requirements of ceramide and sphingosine bas...
T35806 N-Stearoylsphingosine

C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide

Phosphatase Metabolism
N-Stearoylsphingosine (Cer(d18:1/18:0)) 是一种广泛存在真核生物体内的酰胺类化合物,通过干扰PP2A与PP2A抑制剂2的结合来增强蛋白质磷酸酶2A(PP2A)活性,导致Akt去磷酸化。N-Stearoylsphingosine 可用于研究前列腺癌。
T37439 C18 Globotriaosylceramide (d18:1/18:0)

C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosoma...
T37457 C18 L-threo Ceramide (d18:1/18:0)

C18 L-threo Ceramide (d18:1/18:0)

C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.21 mol% (16.8 μM).

化合物

C18 D-threo Ceramide (d18:1/18:0)
Cat.No: T37455
Synonym: C18 D-threo Ceramide (d18:1/18:0)
Target:
N-Stearoylsphingosine
Cat.No: T35806
Synonym: C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide
Target: Phosphatase
C18 Globotriaosylceramide (d18:1/18:0)
Cat.No: T37439
Synonym:
Target:
C18 L-threo Ceramide (d18:1/18:0)
Cat.No: T37457
Synonym: C18 L-threo Ceramide (d18:1/18:0)
Target:
Cat. No. Product Name Species Expression System
TMPY-02019 CD59 Protein, Human, Recombinant (His)

MIN2,MAC-IP,G344,EL32,FLJ92039,HRF-20,EJ30...

Human HEK293 Cells
CD59 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P13987-1.
TMPY-03090 CD59 Protein, Rat, Recombinant (hFc)

CD59 molecule,CD59

Rat HEK293 Cells
CD59 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.8 kDa and the accession number is P27274.
TMPY-03091 CD59 Protein, Rat, Recombinant (His)

CD59 molecule,CD59

Rat HEK293 Cells
CD59 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.3 kDa and the accession number is P27274.
TMPY-03640 CD59 Protein, Cynomolgus, Recombinant (His)

CD59,CD59 molecule

Cynomolgus HEK293 Cells
CD59 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is G7PQF7.

重组蛋白

CD59 Protein, Human, Recombinant (His)
Cat.No: TMPY-02019
Species: Human
Expression System: HEK293 Cells
CD59 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03090
Species: Rat
Expression System: HEK293 Cells
CD59 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03091
Species: Rat
Expression System: HEK293 Cells
CD59 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03640
Species: Cynomolgus
Expression System: HEK293 Cells
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