Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17649 |
Boc-GABA-OH
|
Others; PROTAC Linker | Others; PROTAC |
Boc-GABA-OH 是一种 PROTAC linker,可用于 UNC6852 的合成。其中 UNC6852 是靶向 EED 的 PROTAC 降解剂。 | |||
T13765 |
MAK683-CH2CH2COOH
|
Others | Others |
MAK683-CH2CH2COOH 与 EED (胚胎外胚层发育蛋白) 结合。基于MAK683-CH2CH2COOH 和 E3 泛素连接酶的 VHL 配体,设计了靶向EED 的PROTACs, PROTAC EED degrader-1 和 PROTAC EED degrader-2 。 | |||
T17660 |
Boc-NH-PEG1-Ph-O-CH2COOH
|
Others | Others |
Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC Linker which is used for the EED-targeted PROTAC[1]. | |||
T18665 |
(S,R,S)-AHPC-C4-NH2 dihydrochloride
VH032-C4-NH2 dihydrochloride |
Others | Others |
(S,R,S)-AHPC-C4-NH2 dihydrochloride is a chemically derived E3 ligase ligand-linker conjugate, consisting of the (S,R,S)-AHPC VHL ligand and a linker specifically designed for EED-Targeted PROTAC[1]. | |||
T18666 |
(S,R,S)-AHPC-C4-NH2
VH032-C4-NH2 |
Others | Others |
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specifically designed for EED-Targeted PROTAC[1]. | |||
T18663 |
(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)
(S,R,S)-AHPC-C3-NH2 TFA,VH032-C3-NH2 TFA |
Others | Others |
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, suc |