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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T81538 |
Patecibart
|
Endothelin Receptor | GPCR/G Protein |
Patecibart为人源化免疫球蛋白G4-kappa型抗EDNRA单克隆抗体,属于内皮素受体拮抗剂类药物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01294 |
EDNRA Protein, Human, Recombinant (His)
ET-A,Endothelin-1 receptor,hET-AR,ETA-R,ETRA,EDNRA,... |
Human | P. pastoris (Yeast) |
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. | |||
TMPH-01295 |
Endothelin-1/EDN1 Protein, Human, Recombinant (GST)
Preproendothelin-1,EDN1,PPET1,Endothelin-1 |
Human | E. coli |
Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. | |||
TMPH-03286 |
Endothelin-1/EDN1 Protein, Rat, Recombinant (His & KSI)
PPET1,Preproendothelin-1,Endothelin-1,EDN1 |
Rat | E. coli |
Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Endothelin-1/EDN1 Protein, Rat, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 17.8 kDa and the accession number is P22388. |