Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15190L |
(S,R,S)-AHPC-PEG4-NH2
VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) 是一种合成的 E3 连接酶配体-接头偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 4 单元 PEG 接头。 | |||
T17898 |
cIAP1 Ligand-Linker Conjugates 7
E3 ligase Ligand-Linker Conjugates 44 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 7 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. It is utilized in the design of SNIPERs[1]. | |||
T17914 |
Thalidomide-O-amido-C3-COOH
Cereblon Ligand-Linker Conjugates 7,E3 ligase Ligand-Linker Conjugates 15 |
Others | Others |
Thalidomide-O-amido-C3-COOH is a synthesized conjugate of an E3 ligase ligand-linker compound that combines a cereblon ligand derived from Thalidomide with a linker commonly employed in PROTAC technology. | |||
T17910 |
(S,R,S)-AHPC-PEG2-C4-Cl
E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl |
Others | Others |
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1]. | |||
T15190 |
(S,R,S)-AHPC-PEG4-NH2 hydrochloride
E3 ligase Ligand-Linker Conjugates 7,VH032-PEG4-NH2 hydrochloride,VHL Ligand-Linker Conjugates 4 hydrochloride |
Others | Others |
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology. |