搜索结果

Search Results for " e3 ligase ligand 9 "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T17880	E3 ligase Ligand 9	Others	Others
	E3 ligase Ligand 9 is a compound that serves as a ligand for E3 ubiquitin ligase. It can be linked to the protein ligand through a linker, forming PROTACs or SNIPERs. These PROTACs are known to induce the degradation of cancer-promoting proteins through ubiquitination-mediated mechanisms[1].
T7756	Pomalidomide-PEG4-Ph-NH2	Ligand for E3 Ligase	PROTAC
	Pomalidomide-PEG4-Ph-NH2 是一种合成的 E3 连接酶配体- linker 偶联物，结合了基于 Pomalidomide 的 cereblon 配体和 4 单元 PEG linker。
T17920	(S,R,S)-AHPC-PEG1-N3 VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) 是 E3 连接酶配体和linker 连接得到的偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 1 个单元 PEG linker。
T17899	cIAP1 Ligand-Linker Conjugates 9 E3 ligase Ligand-Linker Conjugates 45	Others	Others
	cIAP1 Ligand-Linker Conjugates 9 feature an IAP ligand specifically targeting the E3 ubiquitin ligase, along with a PROTAC linker. It is valuable tools for developing SNIPERs[1].
T17926	(S,R,S)-AHPC-PEG6-C4-Cl VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl	Others	Others
	(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T17890	cIAP1 Ligand-Linker Conjugates 2 Hydrochloride E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base)	Others	Others
	cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1].
T31221	dBRD9 dBRD-9,dBRD 9	PROTACs	PROTAC
	dBRD9是一种 PROTAC。dBRD9是一种双重作用的分子，一部分连接 Bromodomain-containing protein 9 （BRD9）的溴域，另一部分招募小脑 E3泛素连接酶的配体（ligand that recruits the cereblon E3 ubiquitin ligase）。dBRD9对 MOLM-13细胞中 BRD9具有抑制作用，可使其降解，IC50为104 nM。
T9402	Thalidomide-O-C4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-O-C4-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 PROTAC 技术中使用的接头，是一种合成的 E3 连接酶配体-接头偶联物。
T18805	Thalidomide-C2-amido-C2-COOH	Others	Others
	Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of PROTAC CDK2/9 Degrader-1[1].
T36264	(S,R,S)-AHPC-PEG1-NH2 dihydrochloride VH 032 amide-PEG1-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 9 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.