Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7760 |
Thalidomide-O-amido-C3-NH2 TFA
Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA |
E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | PROTAC |
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物,。 | |||
T17874 |
Nutlin carboxylic acid
MDM2 ligand 1,E3 ligase Ligand 16 |
Others | Others |
Nutlin Carboxylic Acid (MDM2 ligand 1), derived from Nutlin 3, serves as an MDM2 ligand. It can be attached to a protein ligand via a linker to create PROTACs[1]. | |||
T18555 |
Pomalidomide-PEG2-Tos
Cereblon Ligand-Linker Conjugates 16,E3 ligase Ligand-Linker Conjugates 52 |
Others | Others |
Pomalidomide-PEG2-Tos is a compound that consists of an E3 ligase ligand-linker conjugate. It is composed of a cereblon ligand conjugated to a two-unit PEG linker[1]. | |||
T18872 |
(S,R,S)-AHPC-PEG5-COOH
VH032-PEG5-COOH,E3 Ligase Ligand-Linker Conjugates 58,VHL Ligand-Linker Conjugates 16 |
Others | Others |
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1]. | |||
T39609 |
cIAP1 Ligand-Linker Conjugates 16
cIAP1 Ligand-Linker Conjugates 16 |
||
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs. |