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Cat. No. Product Name Target Signaling Pathways
T70096 AEG40730 HCl

AEG40730 is a potent and selective IAP antagonist and a BIR-binding tetrapeptide. AEG40730 binds to cIAP1 and cIAP2, facilitates their autoubiquitination and proteosomal degradation, and causes a dramatic reduction in RIP1 ubiquitination. Treatment with nanomolar concentrations of AEG40730 resulted in the loss of both XIAP and c-IAP1 proteins, albeit with different kinetics.

化合物

AEG40730 HCl
Cat.No: T70096
Synonym:
Target:
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