Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6476 |
Dofetilide
UK 68789,UK-68798,Tikosyn,多非利特 |
Potassium Channel | Membrane transporter/Ion channel |
Dofetilide (UK 68789) 是一种具有口服活性、有效的且特异性的IKr 阻滞剂,作为 III 类抗心律失常药物。Dofetilide 可用于心血管疾病研究。 | |||
T11072 |
Dofetilide D4
多非利特 D4,UK 68789 D4 |
Others | Others |
Dofetilide D4 (UK 68789 D4), a deuterium-labeled version of Dofetilide, is categorized as a Class III antiarrhythmic medication. | |||
T11073 |
Dofetilide N-oxide
UK-116856 |
Others | Others |
Dofetilide N-oxide (UK-116856) is a metabolite of dofetilide. Dofetilide can block potassium channels and is a tertiary antiarrhythmic drug. | |||
T16796 |
RPR-260243
|
Others | Others |
RPR-260243 is a novel activator of HERG and modifies HERG currents inhibited by dofetilide (IC50 = 58 nM). |