Cat. No. | Product Name | Target | Signaling Pathways |
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T60751 | Dicyclomine | ||
Dicyclomine (Dicycloverine) 是口服有效的毒蕈碱胆碱能受体拮抗剂,它是一种解痉剂,可缓解体内胃肠道平滑肌痉挛。Dicyclomine 对 M1 受体亚型和 M2 受体亚型具有高亲和力,在刷状缘膜和基底质膜中的Ki 值分别为5.1 nM 和54.6 nM 。 | |||
T1460 |
Dicyclomine hydrochloride
|
AChR | Neuroscience |
Dicyclomine hydrochloride 是口服活性毒蕈碱胆碱能受体拮抗剂。它是一种抗痉挛试剂,在体内可缓解胃肠道平滑肌痉挛。它对 M1 受体亚型和 M2 受体亚型,Ki 分别为5.1和54.6nM,在刷状缘膜和基底质膜中均表现出较高的亲和力。 | |||
T70070 |
Cisapride tartrate
|
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Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisapride was indicated for the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease. The Food and Drug Administration (FDA) in America stopped the marketing of cisapride as of 14th July 2000. They had received at least 341 reports o... |