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Search Results for " deoxythymidine "

16

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1663	Deoxythymidine triphosphate	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Deoxythymidine triphosphate 用于体内 DNA 合成的四种核苷三磷酸之一。
T40467	Deoxythymidine-5'-triphosphate dTTP,脱氧胸苷三磷酸
	Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.
T32816	L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine
	L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine is a bioactive chemical.
TNU1251	5’-Amino-5’-deoxythymidine
	5'-Amino-5'-deoxythymidine is a Nucleoside Derivative - 5'-Deoxy nucleoside; 5'-Modified nucleoside; Amino nucleoside.
TNU1048	3’-Bromo-3’-deoxythymidine
	3'-Bromo-3'-deoxythymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.
T4683	Alovudine 3'-Deoxy-3'-fluorothymidine,3'-脱氧-3-氟胸苷	Antiviral	Immunology/Inflammation
	Alovudine (3'-Deoxy-3'-fluorothymidine) 是一种 DNA 合成的标志物。与18F-Fluorodeoxyglucose (FDG) 相比，它不易受炎症变化的影响，在胰腺癌中，它是更好的生物标志物。
TNU1149	5’-Azido-5’-deoxythymidine
	Nucleoside Derivatives - 5’-Modified nucleosides, Azido-nucleosides; Drugs and Inhibitors; Inhibitor of mycobacterium tuberculosis monophosphate kinase (TMPKmt)
TNU1047	3’-Chloro-3’-deoxythymidine;
	Nucleoside Derivatives - Halo-nucleosides, 2’,3’-Dideoxy nucleosides; Drugs and Inhibitors; Metabolite and related compound B of Zidovudine
TNU1148	4’,5’-Didehydro-5’-deoxythymidine
	4',5'-Didehydro-5'-deoxythymidine is a Nucleoside Derivative - 5'-Modified nucleoside, Didehydro-nucleoside.
T74122	Deoxythymidine-5'-triphosphate sodium hydrate
	Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate 是四种核苷三磷酸之一，可以合成 DNA。
TNU0789	3-epi-Azido-3-deoxythymidine
	3’-N-modified nucleoside; Azido-nucleoside
TNU1229	AZT triphosphate
	AZT triphosphate is a Nucleoside Triphosphate.
T83821	Thymidine-5'-O-(α,β-methylene)diphosphate sodium α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP
	TMP-CP（Thymidine-5’-O-(α,β-methylene)diphosphate）是TDP的一种水解稳定衍生物，同时也是一种thymidine kinase抑制剂（Ki = 23 µM）。它已被用作α,β-methylene-2’-deoxythymidine 5’-triphosphate合成的前体，该合成物是DNA polymerase的一种不可切割底物。
T73837	AZT triphosphate tetraammonium
	AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) tetraammonium 是一种 Zidovudine (AZT) 的活性三磷酸酯代谢产物。AZT triphosphate tetraammonium 具有抗逆转录病毒的活性，并抑制 HIV 复制。AZT triphosphate tetraammonium 还可抑制 HBV 的 DNA 聚合酶。AZT triphosphate tetraammonium 可激活线粒体介导的凋亡 (apoptosis) 途径。
T73824	Thymidine 3',5'-diphosphate tetrasodium
	Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium，为一种选择性抑制剂，主要针对葡萄球菌核酸酶及含1的都铎结构域(SND1，MicroRNA调控复合体RISC亚基)和[3,5-2H2]酪氨酸核酸酶([3,5-2H2] tyrosyl nuclease)。此化合物还展示了抗肿瘤活性，并可在生化反应中作为催化剂使用。
T36490	AZT triphosphate TEA
	AZT triphosphate TFA (3'-Azido-3'-deoxythymidine-5'-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TFA also inhibits the DNA polymerase of HBV. AZT triphosphate TFA activates the mitochondria-mediated apoptosis pathway[1][2][3]. Treatment with 100 μM Zidovudine (AZT) for 48h disrupts the mitochondrial tubular network via accumulation of AZT triphosphate (AZT-TP) in ...

化合物

Deoxythymidine triphosphate

Cat.No: T1663

Target: DNA/RNA Synthesis

Deoxythymidine-5'-triphosphate

Cat.No: T40467

Synonym: dTTP,脱氧胸苷三磷酸

L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine

Cat.No: T32816

5’-Amino-5’-deoxythymidine

Cat.No: TNU1251

3’-Bromo-3’-deoxythymidine

Cat.No: TNU1048

Cat.No: T4683

Synonym: 3'-Deoxy-3'-fluorothymidine,3'-脱氧-3-氟胸苷

Target: Antiviral

5’-Azido-5’-deoxythymidine

Cat.No: TNU1149

3’-Chloro-3’-deoxythymidine;

Cat.No: TNU1047

4’,5’-Didehydro-5’-deoxythymidine

Cat.No: TNU1148

Deoxythymidine-5'-triphosphate sodium hydrate

Cat.No: T74122

3-epi-Azido-3-deoxythymidine

Cat.No: TNU0789

AZT triphosphate

Cat.No: TNU1229

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

Cat.No: T83821

Synonym: α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP

AZT triphosphate tetraammonium

Cat.No: T73837

Thymidine 3',5'-diphosphate tetrasodium

Cat.No: T73824

AZT triphosphate TEA

Cat.No: T36490

Cat. No.	Product Name	Target	Signaling Pathways
T9086	Deoxythymidine-5'-triphosphate trisodium dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate(dTTP) trisodium salt) 是四种天然脱氧核苷酸之一，用于通过 DNA 聚合酶和逆转录酶生物合成脱氧核糖核酸。
T21552	5-deoxy Thymidine 5'-脱氧胸苷,5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione	Others	Others
	5-deoxy Thymidine (5'-Deoxythymidine) 是5'位被氢取代的胸苷形式。它对枯草芽孢杆菌和金黄色葡萄球菌的活性有效。
T20041	2'-Deoxyadenosine 2'-脱氧腺苷,NSC-141848,NSC141848,NSC 141848	Endogenous Metabolite	Metabolism
	2'-Deoxyadenosine (NSC-141848) 是核苷腺苷的一种衍生物，能够与双链 DNA 中的脱氧胸苷配对。
T4735	2'-Deoxyuridine 5'-monophosphate disodium 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt 能够被双底物酶胸苷酸合酶(TS) 还原甲基化为 dTMP (2'-deoxythymidine 5'-monophosphate)。其中 dTMP 是 DNA 合成所需的核苷酸。

天然产物

Deoxythymidine-5'-triphosphate trisodium

Cat.No: T9086

Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

Target: DNA/RNA Synthesis

5-deoxy Thymidine

Cat.No: T21552

Synonym: 5'-脱氧胸苷,5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione

Target: Others

2'-Deoxyadenosine

Cat.No: T20041

Synonym: 2'-脱氧腺苷,NSC-141848,NSC141848,NSC 141848

Target: Endogenous Metabolite

2'-Deoxyuridine 5'-monophosphate disodium

Cat.No: T4735

Synonym: 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt

Target: Others, Endogenous Metabolite

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